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  • RefKA: A fast and efficient long-read genome assembly approach for large and complex genomes

RefKA: A fast and efficient long-read genome assembly approach for large and complex genomes

https://github.com/AppliedBioinformatics/RefKA

RefKA, a reference-based approach for long read genome assembly. This approach relies on breaking up a closely related reference genome into bins, aligning k-mers unique to each bin with PacBio reads, and then assembling each bin in parallel followed by a final bin-stitching step.