cancer.sanger.ac.uk - The accurate description and annotation of structural variants can be complex. This is due to the different resolution that variants are reported from traditional cytogenetic coordinates down to the actual base pair positions....
depmap.sanger.ac.uk - The consequences of alterations in the DNA of cancer cells and subsequent vulnerabilities are not fully understood. This project aims to assign a dependency to every cancer cell in a patient which could be exploited to develop new therapies. This...
Our lab has been interested in understanding how long noncoding RNAs control tumor initiation and progression, in addition to use them as potential biomarkers in diagnosis and therapy. We have been using neuroblastoma, a childhood cancer, as a model...
Shirley is a computational biologist with expertise in cancer epigenetics. Her research focuses on algorithm development and integrative mining from big data generated on microarrays, massively parallel sequencing, and other high throughput...
pbil.univ-lyon1.fr - DeCoSTAR is a software which aims at reconstructing ancestral gene or genome organizations, in the form of sets of neighborhood relations -adjacencies- between pairs of ancestral genes or gene domains.Ancestral genes or domains are deduced from...
Transposable Elements (TEs) to genome structure and evolution as well as their impact on genome sequencing, assembly, annotation and alignment has generated increasing interest in developing new methods for their computational analysis.
Following...
github.com - platypus is an R package for object detection and semantic segmentation. Currently using
platypus you can perform:
multi-class semantic segmentation using U-Net architecture
multi-class object detection...
static.ciscall.org - cisMuton is a caller that detects SNVs/indels by comparing target (foreground) and control (background) samples.
cisMuton calls mutations from target capture regions, which are defined by the overlapping regions...
kiwi.cs.dal.ca - RITA is a standalone software package and Web server for taxonomic assignment of metagenomic sequence reads. By combining homology predictions from BLAST or UBLAST with compositional classifications from a Naive Bayes classifier, RITA is able to...
Is reference genome necessary for gene expression study in transcriptome sequencing or for variant discovery in genome sequencing?