To decide which strategy should be our “preferred” genome assembly approach based on data rather than my gut-feeling about the “best assembly” I decided to do some testing with a known “true” reference E Coli K12 MG1655
There are two methods for ancient WGD detection, one is collinearity analysis, and the other is based on the Ks distribution map. Among them, Ks is defined as the average number of synonymous substitutions at each synonymous site, and there is...
github.com - RagTag is a collection of software tools for scaffolding and improving modern genome assemblies. Tasks include:
Homology-based misassembly correction
Homology-based assembly scaffolding and patching
Scaffold merging
There are numerous genome assembly tools available, each with its strengths and weaknesses. Here is a list of some widely used genome assembly tools as of my last update in September 2021:
SPAdes: An assembler specifically designed for...
The LabEx BASC (Biodiversity, Agroecosystems, Society, Climate), a network of 13 laboratories of the Paris-Saclay Scientific Cluster, is seeking a bioinformatician to analyze Next Generation Sequencing (NGS) data analysis. In the context of a...
BIOINFORMATICS POSTDOC IN FUNCTIONAL EVOLUTIONARY GENOMICS
Center for Integrative Genomics, University of Lausanne, Switzerland
Two postdoctoral positions (2 years with possible extensions up to 5 years) are available immediately in the...
NATIONAL BUREAU OF ANIMAL GENETIC RESOURCES
Near Basant Vihar G.T. Road Bypass
P.O. Box No.129, Karnal-132001 (Haryana)
WALK-IN-INTERVIEW
A walk-in-Interview is proposed to be held at National Bureau of Animal Genetic Resources, Karnal...
ICRISAT is seeking applications from Indian Nationals for a Special Project Scientist to work on a sorghum genomics activities related to sequencing/re-sequencing projects utilizing New Generation Sequencing platforms.
The Job detail...
With the emergence of NGS technologies, and sequencing data most of the bioinformaticians mung and wrangle around massive amounts of genomics text. There are several "standardized" file formats (FASTQ, SAM, VCF, etc.) and some tools for manipulating...