This research group brings the tools of systems biology to bear on the grand challenges of sustainability. The lab members and I are passionate about trying to understand the cellular highways of energy and carbon transformations known as central carbon metabolism in quantitative terms. They employ a combination of computational and experimental synthetic biology tools. Ron Milo Lab research efforts are the culmination of three directions: (1) Understanding the structure and logic of central carbon and energy metabolism in quantitative terms (2) Synthetic metabolic pathways for carbon fixation (3) Novel tools facilitating accurate, accessible and collaborative quantitative cell biology