Useful links to therapy, disease, drug and drug-target network data:
Useful links to therapy, disease, drug and drug-target network data: DrugBank: a bioinformatics- cheminformatics resource combining detailed drug data with comprehensive drug target information with >4900 drug (~3500 experimental) and >1500 non-redundant protein entries http://www.drugban...Tags: resources, therapy, disease, drug, drug-target, network, data
1427 days ago
proActiv: Estimation of Promoter Activity from RNA-Seq data
proActiv is an R package that estimates promoter activity from RNA-Seq data. proActiv uses aligned reads and genome annotations as input, and provides absolute and relative promoter activity as output. The package can be used to identify active promoters and alternative promoters, the details of ...Tags: proActiv, Estimation, Promoter, Activity, RNA-Seq, data
1355 days ago
Tags: McClintock, Meta-pipeline, identify, transposable, element, insertions, next, generation, sequencing, data
1280 days ago
DADA2: Fast and accurate sample inference from amplicon data with single-nucleotide resolution
The DADA2 tutorial goes through a typical workflow for paired end Illumina Miseq data: raw amplicon sequencing data is processed into the table of exact amplicon sequence variants (ASVs) present in each sample. The DADA2 Workflow on Big Data goes through workflow op...Tags: DADA2, Fast, accurate, sample, inference, amplicon, data, single-nucleotide, resolution
1265 days ago
MAGIC: A tool for predicting transcription factors and cofactors driving gene sets using ENCODE data
The algorithm presented herein, Mining Algorithm for GenetIc Controllers (MAGIC), uses ENCODE ChIP-seq data to look for statistical enrichment of TFs and cofactors in gene bodies and flanking regions in gene lists without an a priori binary classification of genes as...Tags: MAGIC, tool, predicting, transcription, factors, cofactors, driving, gene, sets, ENCODE, data
1249 days ago
Tags: 3DGenome, Browser, explore, chromatin, interaction, data, Hi-C, ChIA-PET, Capture, Hi-C, PLAC-Seq
1192 days ago
GraphUnzip: Phases an assembly graph using Hi-C data and/or long reads.
GraphUnzip, a fast, memory-efficient and accurate tool to unzip assembly graphs into their constituent haplotypes using long reads and/or Hi-C data. As GraphUnzip only connects sequences in the assembly graph that already had a potential link based on overlaps, it yields high-quality gap-less sup...Tags: GraphUnzip, Phases, assembly, graph, Hi-C, data, long reads
1178 days ago
Ktrim: an extra-fast and accurate adapter- and quality-trimmer for sequencing data
Ktrim is written in C++ for GNU Linux/Unix platforms. After uncompressing the source package, you can find an executable file ktrim under bin/ directory compiled using g++ v4.8.5 and linked with libz v1.2.7 for Linux x86_64 system. If you cou...Tags: Ktrim, extra-fast, accurate, adapter, quality, trimmer, sequencing, data
1172 days ago
LoReTTA, a user-friendly tool for assembling viral genomes from PacBio sequence data
LoReTTA (Long Read Template-Targeted Assembler), a tool designed for performing de novo assembly of long reads generated from viral genomes on the PacBio platform. LoReTTA exploits a reference genome to guide the assembly process, an approach that has been successful with short reads. https://ac...Tags: LoReTTA, user-friendly, tool, assembly, viral, genomes, PacBio, sequence, data
1041 days ago
Refseq viraal genome sequences !
List of all viruses on NCBI https://ftp.ncbi.nlm.nih.gov/refseq/release/viral/Tags: nvbi, viruses, genome, data, ftp
870 days ago