Assembly and diploid architecture of an individual human genome via single-molecule technologies
The research work shows that it is now possible to integrate single-molecule and high-throughput sequence data to generate de novo assembled genomes that approach refer...3215 days ago
1086 days ago
2867 days ago
2811 days ago
Nemo – A stochastic, individual-base, genetically explicit simulation platform
...effects of linkage can thus be finely explored. A new trait coding for (Bateson-)Dobzhansky-Muller incompatibility loci. Multiple haploid or diploid pairs of incompatible loci ca...2767 days ago
Maq: Mapping and Assembly with Quality
...Download maq, maq-data and maqview at the download page. Copy maq, maq.pl and maq_eval.pl to the $PATH or to the same directory. Simulate diploid reference and read sequences,...2715 days ago
dipSPAdes: Assembler for Highly Polymorphic Diploid Genomes.
While the number of sequenced diploid genomes have been steadily increasing in the...ew years, assembly of highly polymorphic (HP) diploid genomes remains challenging....ves on the state-of-the-art assemblers for HP diploid genomes.2322 days ago
HapCUT2: robust and accurate haplotype assembly for diverse sequencing technologies
...examples of command line options and best practices for some of these technologies. NOTE: At this time HapCUT2 is for diploid organisms only. VCF input should contain diploid variants. If you use HapCU...2176 days ago
2092 days ago
2041 days ago