BioStar
Bioinformatician
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HaploMerger2: rebuilding both haploid sub-assemblies from high-heterozygosity diploid genome assembly
By BioStar 2040 days ago
https://github.com/mapleforest/HaploMerger2/releases/
HM2 can process any diploid assemblies, but it is especially suitable for diploid assemblies with high heterozygosity (≥3%), which can be difficult for other tools. This pipeline also implements flexible and sensitive assembly error detection, a hierarchical scaffolding procedure and a reliable gap-closing method for haploid sub-assemblies.
Source code, executables and the testing dataset are freely available at https://github.com/mapleforest/HaploMerger2/releases/.
