...called profile HMMs (refs). Since then I have applied HMMs to membrane proteins (refs) and gene identificati...ing RNA, where miRNAs and structure prediction are the main areas; and protein structure, where the group is...
...icrobial peptides with membranes: structure and dynamics
Interactions between antimicrobial peptides in the presence of different membranes
Protein-protein interactions
Effects of muta...
...lication of new statistical methods with a focus on the detection of gene-gene interactions associated with human disease.
Gene expression and protein expression patterns between n...
...methods to improve the annotation of functional biological features in genome sequences. Bergman Lab work focuses on improving annotation of non-protein-coding regions of the genome...
...of metabolic pathways from genomic and post-genomic data
(metabolic pathfinding, see also metabolic pathfinding in NeAT)
Critical assesment of protein interactions (CAPRI)
Lab P...
DbBrowser: Attwood Lab research concerns protein sequence analysis, primarily using the method of protein 'fingerprinting'. DbBrowser: Attwood Lab maintain a diagnostic fingerprint database (PRINTS), one of the f...
...e failure might produce developmental defects in model systems.
Research Interest
Genomic Data Integration
Microarray Analysis
Gene and Protein Function Prediction
Detect...
...e and human populations.
Alternative splicing and its relationship to protein interaction networks.
Integrating large-scale studies including phenotype, genetic epistasis, protein-protein and transcription-reg...
...ined as the GABi scope are described next:
Sequence Analysis
Protein Structure Prediction
Comparative Genomics
Functional Analysis of Residues on Protein Families
Gene/Protein Ne...
...tween cell biology, ecological genomics, systems biology, molecular evolution and population genetics. We study the architecture and evolution of protein and signalling networks.
M...