Best practices in bioinformatics training for life scientists
Among life scientists, from clinicians to environmental researchers, a common theme is the need not just to use, and g...tics tools and resources but also to understand their underlying fundamental theoretic...3938 days ago
CAR: Reconstructing Contiguous Regions of an Ancestral Genome
We describe a new method for predicting the ancestral order and orientation of those intervals from their observed a...only a few mammalian genomes are currently sequenced to high precision, our theoretic...2565 days ago
MUMmer4: A fast and versatile genome alignment system
MUMmer4, a substantially improved version of MUMmer that addresses genome size constraints by changing the 32-bit suff...improved speed through parallel processing of input query sequences. With a theoretic...2304 days ago
Reference-free prediction of rearrangement breakpoint reads
lideSort-BPR ( b reak p oint r eads) is based on a fast algorithm for all-against-all comparisons of short reads and theoretic...2271 days ago
QUAST-LG: Versatile genome assembly evaluation
QUAST-LG-a tool that compares large genomic de novo assemblies against reference sequences...for a given genome and set of reads, and compute theoretical limits on assembly correctnes...-LG, we show how close the assemblies are to the theoretic...2039 days ago
BLAST options, setting and defaults
BLAST stands for Basic Local Alignment Search Tool and was developed by Altschul et al. (1990) and significantly impro...de to BLAST searching can be found at the NCBI BLAST Help Manual. For a theoretic...1993 days ago
SiLiX: implements an ultra-efficient algorithm for the clustering of homologous sequences
The software package SiLiX implements an ultra-efficient algorithm for the clustering of homologous sequences, ba...(single linkage) with alignment coverage constraints. SiLiX adopts a graph-theoretic...1991 days ago
Versatile genome assembly evaluation with QUAST-LG
QUAST-LG is an extension of QUAST intended for evaluating large-scale genome assemblies (up to mammalian-siz...enhanced reference-free analysis The concept of upper bound assembly (theoretic...1982 days ago
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