Results for "Tool"

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  • LSC :a long read error correction tool

    Getting Started These simple steps will help you integrate LSC into your transcriptomics analysis pipeline. Read the LSC_requirements for running LSC. Download and set-up the LSC package. Follow the tutorial to see how LSC works on some example data. Read the ...

    Tags: LSC, long, read, error, correction, tool, fast, correction, sensitivity, good, accuracy

    2095 days ago

  • gSearch: a fast and flexible general search tool for whole-genome sequencing

    gSearch compares sequence variants in the Genome Variation Format (GVF) or Variant Call Format (VCF) with a pre-compiled annotation or with variants in other genomes. Its search algorithms are subsequently optimized and implemented in a multi-threaded manner. 

    Tags: gSearch, fast, flexible, search, tool, whole-genome, sequencing

    2091 days ago

  • AlignQC: A tool for assessing an alignment, and generating reports that are easy to share

    Long read alignment analysis. Generate a reports on sequence alignments for mappability vs read sizes, error patterns, annotations and rarefraction curve analysis. The most basic analysis only requires a BAM file, and outputs a web browser compatible xhtml to visualize/share/store/extract analysi...

    Tags: AlignQC, tool, assessing, alignment, reports, easy, share, NGS, reads

    2090 days ago

  • FMLRC: a long-read error correction tool using the multi-string Burrows Wheeler Transform

    FMLRC, or FM-index Long Read Corrector, is a tool for performing hybrid correction of long read sequencing using the BWT and FM-index of short-read sequencing data. Given a BWT of the short-read sequencing data, FMLRC will build an FM-index and use that as an implicit de Bruijn graph. Each long r...

    Tags: FMLRC, long-read, error, correction, tool, multi-string, Burrows, Wheeler, Transform, nanopore

    2087 days ago

  • FinisherSC:a repeat-aware tool for upgrading de novo assembly using long reads

    Here is the command to run the tool: python finisherSC.py destinedFolder mummerPath If you are running on server computer and would like to use multiple threads, then the following commands can generate 20 threads to run FinisherSC. python finisherSC.py -par 20 destinedFolder mummerPath S...

    Tags: FinisherSC, repeat-aware, tool, upgrading, de novo, assembly, long, reads

    2077 days ago

  • LRCstats: a tool for evaluating long reads correction methods

    LRCstats is an open-source pipeline for benchmarking DNA long read correction algorithms for long reads outputted by third generation sequencing technology such as machines produced by Pacific Biosciences. The reads produced by third generation sequencing technology, as the name suggests, are lon...

    Tags: LRCstats, tool, evaluation, long, reads, correction, methods

    2075 days ago

  • LoRMA: A tool for correcting sequencing errors in long reads

    An error correction method that uses long reads only. The method consists of two phases: first, we use an iterative alignment-free correction method based on de Bruijn graphs with increasing length of k-mers, and second, the corrected reads are further polished using long-distance dependenci...

    Tags: LoRMA, tool, correction, sequencing, errors, long, reads, PacBio, SMRT

    2060 days ago

  • SeqMonk:A tool to visualise and analyse high throughput mapped sequence data

    SeqMonk is a program to enable the visualisation and analysis of mapped sequence data. It was written for use with mapped next generation sequence data but can in theory be used for any dataset which can be expressed as a series of genomic positions. It's main features are: Import of mapped da...

    Tags: SeqMonk, tool, visualise, analyse, high, throughput, mapped, sequence, data

    2055 days ago

  • rHAT: a seed-and-extension-based noisy long read alignment tool

    rHAT is a seed-and-extension-based noisy long read alignment tool. It is suitable for aligning 3rd generation sequencing reads which are in large read length with relatively high error rate, especially Pacbio's Single Molecule Read-time (SMRT) sequencing reads.

    Tags: rHAT, seed-and-extension-based, noisy, long, read, alignment, tool, ont, pacbio

    2043 days ago

  • GRSR: a tool for deriving genome rearrangement scenarios from multiple unichromosomal genome sequences

    GRSR is a Tool for Deriving Genome Rearrangement Scenarios for Multiple Uni-chromosomal Genomes. This tool will do the following steps: Step 1. Run mugsy to get multiple sequence alignment results. Step 2 & 3. Extraction of the Coordinates of Core Blocks, Construction of Synteny Blocks an...

    Tags: GRSR, tool, genome, rearrangement, scenarios, multiple, unichromosomal, genome, sequences

    2038 days ago