Results for "assembly"

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  • CABOG: Celera Assembler with Best Overlap Graph

    CABOG (Celera Assembler with Best Overlap Graph) is scientific software for DNA research. CABOG has been a critical component of many genome sequencing projects. CABOG operates on small genomes such as bacterial as well as large genomes such as mammalian. CABOG is an extension of the Celera ...

    Tags: CABOG, Celera, Assembler, Overlap Graph, Bioinformatics, Assembly, Genome, Reads, NGS

    2561 days ago

  • NCBI Prokaryotic Genome Annotation Pipeline

    NCBI Prokaryotic Genome Annotation Pipeline is designed to annotate bacterial and archaeal genomes (chromosomes and plasmids). Genome annotation is a multi-level process that includes prediction of protein-coding genes, as well as other functional genome units such as structural RNAs, tRNAs, sma...

    Tags: Bioinformatics, Analysis, Assembly, Genome, Annotation, NCBI, Pipeline, Prokaryotes

    2559 days ago

  • BIGMAC : breaking inaccurate genomes and merging assembled contigs for long read metagenomic assembly

    This tool is for users to upgrade their metagenomics assemblies using long reads. This includes fixing mis-assemblies and scaffolding/gap-filling. If you encounter any issues, please contact me at kklam@eecs.berkeley.edu. My name is Ka-Kit Lam. https://github.com/kakitone/MetaFinisherSC ht...

    Tags: BIGMAC, Breaking, Inaccurate, Genomes, Merging, Assembled, Contigs, Long, Read, Metagenomic, Assembly

    2554 days ago

  • SIMBA: a web tool for managing bacterial genome assembly generated by Ion PGM sequencing technology

    SIMBA, SImple Manager for Bacterial Assemblies, is a Web interface for managing assembly projects of bacterial genomes. SIMBA was created to assist bioinformaticians to assemble bacterial genomes sequenced with NextGeneration Sequencing (NGS) platforms quickly, easily and effectively. SIMBA also ...

    Tags: SIMBA, Web, Tool, Bacterial, Genome, Assembly, Ion PGM, Sequencing

    2553 days ago

  • Assembly Course

    https://ocw.mit.edu/courses/biology/7-91j-foundations-of-computational-and-systems-biology-spring-2014/lecture-slides/MIT7_91JS14_Lecture6.pdf

    Tags: Assembly, PPT

    2504 days ago

  • Meraculous: De Novo Genome Assembly with Short Paired-End Reads

    We describe a new algorithm, meraculous, for whole genome assembly of deep paired-end short reads, and apply it to the assembly of a dataset of paired 75-bp Illumina reads derived from the 15.4 megabase genome of the haploid yeast Pichia stipitis. More than 95% of the genome is recovered, wi...

    Tags: Meraculous, De Novo, Genome, Assembly, Short, Paired-End, Reads

    2385 days ago

  • Oxford Nanopore Sequencing, Hybrid Error Correction, and de novo Assembly of a Eukaryotic Genome

    Monitoring the progress of DNA molecules through a membrane pore has been postulated as a method for sequencing DNA for several decades. Recently, a nanopore-based sequencing instrument, the Oxford Nanopore MinION, has become available that we used for sequencing the S. cerevisiae genome. To make...

    Tags: Oxford, Nanopore, Sequencing, Hybrid, Error, Correction, de novo, Assembly, Eukaryotic, Genome

    2363 days ago

  • Meraculous: Haplotype-sensitive Assembly of Highly Heterozygous genomes.

    Meraculous is a whole genome assembler for Next Generation Sequencing data geared for large genomes. It is a hybrid k-mer/read-based assembler that capitalizes on the high accuracy of Illumina sequence by eschewing an explicit error correction step which we argue to be redundant with the assembly...

    Tags: Meraculous, Haplotype-sensitive, Assembly, Highly, Heterozygous, genomes, Meraculous-2D

    2341 days ago

  • Rectangle Graph for Repeat Resolution in Genome Assembly

    Ultimate tool for resolving repeats in genome assemblies. Though the specific implementation of the idea of the rectangle graph approach is already included into the current SPAdes distribution, we're also releasing the Rectangle Graph Module (RGM) as the separate code which can be run inde...

    Tags: Rectangle, Graph, Repeat, Resolution, Genome, Assembly

    2333 days ago

  • HINGE: Long-Read Assembly Achieves Optimal Repeat Resolution

    Software accompanying "HINGE: Long-Read Assembly Achieves Optimal Repeat Resolution" Preprint: http://biorxiv.org/content/early/2016/08/01/062117 Paper: http://genome.cshlp.org/content/27/5/747.full An ipython notebook to reproduce results in the paper can be found in thi...

    Tags: HINGE, Long-Read, Assembly, Achieves, Optimal, Repeat, Resolution

    2292 days ago