We study mechanisms of cancer evolution by using state-of-the-art genomic approaches at the bench and in analysis. Accurate genome reconstruction is our other major area of interest. W...
...lls within tumours in ever greater detail, teasing out patterns of evolution (evolutionary rule books), cancer hetero...stigating the processes that cause mutations and accelerate tumour evolution and working out how they migh...
...ative genomic and epigenomic analyses. Areas of interest include: the evolution of regulatory sequences, the...lements in gene regulation and the impact of genome rearrangements in evolution and cancer.
As a computati...
The Rogers lab studies evolution of genome structure. We explore the ways that complex mutations like duplications, deletions, rearrangements, and retrogenes can create new genetic...
Study the process of Adaptive Evolution, during which species adopt novel traits to overcome challenges. We retrace the evolutionary histories of genomic eleme...
We are a bioinformatics research lab focused on developing novel methods and using them to study genome evolution, organization, and regulation. Our mission is to decode biomedical kno...
My main topics of interest are:
The impact of non tree-like evolution such as horizontal gene transfers and hybridization on species biology
Evolution and adaptation of animals in...
...these high quality genomes we explore
the evolutionary history of genes and speci...l gene transfer and introgression in shaping evolution
the biology of symbioses, es...nd their hosts
the processes that drive the evolution of pattern in the structure o...
We investigate genome evolution across the plant kingdom at diffe...omosome rearrangements, karyotype evolution)
•Genomes (genome collineari...ciation, phylogenomics)
Genome evolution in crucifers (Brassicaceae) i...centromere shift and elimination, evolution of repetitive sequences, and...
...s changing today. Hence, they are trying to understand the process of evolution, with mathematical models and...ences between them, are a crucial source of information to understand evolution and biology in general. They...