PilonGrid: parallel wrapper around the Pilon framework
The distribution is a parallel wrapper around the Pilon framework The pipeline is composed of bash scripts, an example mapping.fofn which shows how to input your fastq files (you give paths to the R1 file), and how to launch the pipeline.Tags: PilonGrid, parallel, wrapper, Pilon, framework
1964 days ago
Biotite: A general framework for computational biology
The package is open source and freely available at GitHub (https://github.com/biotite-dev/biotite). This package is simple to use especially for the beginners in programming and computationally efficient because of the implementation of Numpy and Cython. Biotite consists of four sub packages...Tags: Biotite, general, framework, computational, biology
1960 days ago
nQuire: A statistical framework for ploidy estimation using NGS short-read data
nQuire implements a set of commands to estimate ploidy level of individuals from species, where recent polyploidization occurred and intraspecific ploidy variation is observed. Specifically, nQuire uses next-generation sequencing data to distinguish between diploids, triploids and tetraploids, on...Tags: statistical, framework, ploidy, estimation, NGS, short-read, data
1915 days ago
ChIPulate: A Python3 framework to simulate read counts in a ChIP-seq experiment
ChIP-seq simulation pipeline, ChIPulate, we assess the impact of various biological and experimental sources of variation on several outcomes of a ChIP-seq experiment, viz., the recoverability of the TF binding motif, accuracy of TF-DNA binding detection, the sensitivity of inferred TF-DNA bindin...Tags: ChIPulate, Python3, framework, simulate, read, counts, ChIP-seq, experiment
1862 days ago
ALF--a simulation framework for genome evolution.
Artificial Life Framework (ALF) simulates a root genome into a number of related genomes. Result files include the resulting gene sequences, true tree and true MSAs. A description of ALF can be found in the following article: Daniel A Dalquen, Maria Anisimova, Gaston H Gonnet, Christophe Dessimo...Tags: ALF, simulation, framework, genome, evolution
1651 days ago
Tags: Dash, web, application, framework, Python, abstraction, HTML, CSS, JavaScript
1637 days ago
RosettaAntibodyDesign (RAbD): A general framework for computational antibody design
RosettaAntibodyDesign (RAbD) is a generalized framework for the design of antibodies, in which a user can easily tailor the run to their project needs. The algorithm is meant to sample the diverse sequence, structure, and binding space of an antibody-antigen complex. It can be used...Tags: RosettaAntibodyDesign, RAbD, framework, computational, antibody, design, rosetta
1317 days ago
UniAligner: a parameter-free framework for fast sequence alignment
UniAligner (formerly, TandemAligner) is the first parameter-free algorithm for sequence alignment that introduces a sequence-dependent alignment scoring that automatically changes for any pair of compared sequences. Classical alignment approaches, such as the Smith-Waterman algorithm, that work w...Tags: UniAligner, parameter-free, framework, fast, sequence, alignment
51 days ago