RNA Sequencing Helps Identify Functional Variants from GWAS
For Alzheimer’s and other complex disorders, mining the genome for disease-associated variants is no longer the obstacle. The challenge nowadays is figuring out how...3820 days ago
Bioinformatics software for biologists in the genomics era
...lux of DNA sequence data has encouraged laboratory scientists to engage large datasets in comparative sequence analyses for making evolutionary, functional and translational inferences....3791 days ago
7th International Conference on Bioinformatics and Computational Biology (BICoB)
...rative genomics. Sequence analysis: Multiple sequence alignment, sequence search and clustering, function prediction, motif discovery, functional site recognition in protein,...3503 days ago
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PolyPhen-2: Prediction of functional effects of human nsSNPs
PolyPhen-2 (Polymorphism Phenotyping v2) is a tool which predicts possible impact of an amino acid substitution on the structure and function of a human protein using straightforward physical and comparative considerations.2909 days ago
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Method in Comparative genomics !!
...ed species. We observed the pressure to conserve the reading frame of functional proteins and developed a test...orthy novel motifs. The majority of discovered motifs are enriched in functionally related genes, allowing us...2738 days ago