2357 days ago
Computational Genomics: Applied Comparative Genomics
The primary goal of the course is for students to be grounded in theory and leave the...amp; analysis, gene expression & regulation, personal genome analysis, and cancer genomics. The grading will be...2348 days ago
Reference-free prediction of rearrangement breakpoint reads
lideSort-BPR ( b reak p oint r eads) is based on a fast...orrectly with no false-positive reads. Moreover, evaluation on a real prostate cancer dataset shows that the propos...2249 days ago
2168 days ago
Platypus: A Haplotype-Based Variant Caller For Next Generation Sequence Data
Platypus is a tool designed for efficient and accurate variant-detection in high...cts, and is being used in clinical sequencing trials in the Mainstreaming Cancer Genetics programme. ...2018 days ago
1542 days ago
SVEngine: Allele Specific and Haplotype Aware Structural Variants Simulator
SVEngine (Structural Variants Engine) SVEngine is a multi-purpose and self-contain...iles (see Manual) and NEWICK files for specifying clonal phylogenetic trees in cancer. SVEngine outpus alterred co...1400 days ago
MAGIC: A tool for predicting transcription factors and cofactors driving gene sets using ENCODE data
The algorithm presented herein, Mining Algorithm for GenetIc Controllers (MAGIC), uses ENCODE C...changes in 4 settings: 1) A cell line expressing or lacking single TF, 2) Breast...1255 days ago
maftools : Summarize, Analyze and Visualize MAF Files
With advances in Cancer Genomics, Mutation Annotation Format (MAF) is be...pted and used to store somatic variants detected. The Cancer Genome Atlas Project has sequenced over 30 different cancers with sample size of each can...1228 days ago
869 days ago