Kraken: ultrafast metagenomic sequence classification using exact alignments
...chers to use faster abundance estimation programs, which only classify small subsets of metagenomic data. Using exact alignment of k-mers, Kraken achieves classification accuracy compa...2860 days ago
Meraculous: Haplotype-sensitive Assembly of Highly Heterozygous genomes.
...accuracy of Illumina sequence by eschewing an explicit error correction step which we argue to be redundant with the assembly process. Meraculous achieves high performance with large d...2318 days ago
HINGE: Long-Read Assembly Achieves Optimal Repeat Resolution
Software accompanying "HINGE: Long-Read Assembly Achieves Optimal Repeat Resolution" Preprint: http://biorxiv.org/content/early/2016/08/01/062117 Paper: http://geno...2270 days ago
MMseqs2.0: ultra fast and sensitive protein search and clustering suite
...to run on multiple cores and servers and exhibits very good scalability. MMseqs2 can run 10000 times faster than BLAST. At 100 times its speed it achieves almost the same sensitivity....2227 days ago
Scallop: reference-based transcriptome assembler for RNA-seq
...multi-exon transcripts as well as lowly expressed transcripts. Scallop achieves this improvement through a no...eserving all phasing paths from reads and paired-end reads, while also achieves both transcripts parsimony an...2180 days ago
FastANI: fast alignment-free computation of whole-genome Average Nucleotide Identity (ANI)
...identity estimates. Based on our experiments with complete and draft genomes, its accuracy is on par with BLAST-based ANI solver and it achieves two to three orders of magnit...2114 days ago
Platypus: A Haplotype-Based Variant Caller For Next Generation Sequence Data
...signed for efficient and accurate variant-detection in high-throughput sequencing data. By using local realignment of reads and local assembly it achieves both high sensitivity and hig...2010 days ago
MSAProbs - Parallel and accurate multiple sequence alignment
...partition functions to calculate posterior probabilities. Assessed using the popular benchmarks: BAliBASE, PREFAB, SABmark and OXBENCH, MSAProbs achieves statistically significant acc...1752 days ago
Seq: A high-performance, Pythonic language for bioinformatics
...nd a host of domain-specific features and optimizations, Seq makes writing high-performance genomics software as easy as writing Python code, and achieves performance comparable to (an...1616 days ago
URMAP, an ultra-fast read mapper
...arable accuracy on several validation tests. On a Genome in a Bottle (GIAB) variant calling test with 30× coverage 2×150 reads, URMAP achieves high accuracy (precision 0.99...1274 days ago