Hi Govardhan,
I guess from above mentioned genome size that you are working on prokaryotes genome and looking for a tool to predict the origin and terminus of replication. I hope following tool will be helpful for your research.
Oriloc:...
Hi Govardhan,
If the protein or nucleotide sequences are known then you can use BLAST. It is better to perform searches at the protein level, either with translations of the nucleotide sequences or by direct protein-protein BLAST. This is because...