A2Amapper: ATAC, Assembly to Assembly Comparision tool:
Comparative mapping between two genome assemblies (same species), or between two different genomes (cross species).
Sim4db:
Spliced alignment of cDNA and genomic sequences, from the same (sim4) or related (sim4cc) species. Optimized for high-throughput batched alignment.
LEAFF:
LEAFF (ahem, Let's Extract Anything From Fasta) is a utility program for working with multi-fasta files. In addition to providing random access to the base level, it includes several analysis functions.
Meryl:
An out-of-core k-mer counter. The amount of sequence that can be processed for any size k depends only on the amount of free disk space.