Rahul Nayak
A Bioinformatician
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Genomics and sequencing approach for identification of biomarkers to assess the efficacy of TGF-βRI...
By Rahul Agarwal 3765 days agoLiver cancer is third leading cause of deaths and fourth most frequent occuring cancer worldwide. There are multiple signaling pathways responsible for causing cancer amongst which TGFb is most important cytokine whose signaling pathway promote...simNGS and simLibrary – Software for Simulating Next-Gen Sequencing Data
By Jit 2554 days agowww.ebi.ac.uk - simNGS is software for simulating observations from Illumina sequencing machines using the statistical models behind the AYB base-calling software. By default, observations only incorporate noise due to sequencing and do not incorporate effects from...vt: a variant tool set that discovers short variants from Next Generation Sequencing data.
By Jit 1763 days agogenome.sph.umich.edu - vt is a variant tool set that discovers short variants from Next Generation Sequencing data. https://genome.sph.umich.edu/wiki/Vt https://github.com/atks/vt
Structure of Binary files used for storing sequencing data-bam and sff
Last updated 4124 days ago by Rahul AgarwalMany times bioinformatician needs to parse binary files like bam and sff. Advantage of binary files is that they occupy less space in memory with maximum information content. Link for those who looking for structure of Bam and sff...The First 50 Plant Genomes
By Rahul Agarwal 4053 days agowww.crops.org - Plant scientists can exploit available 50 plant complete genomic data for their resequencing or other related projects for understanding the genetic mechanism behind their different traits and molecular evolution. Complete information about these...GeneProf: analysis of high-throughput sequencing experiment
By Jit 2700 days agowww.geneprof.org - GeneProf is a web-based, graphical software suite that allows users to analyse data produced using high-throughput sequencing platforms (RNA-seq and ChIP-seq; "Next-Generation Sequencing" or NGS): Next-gen analysis for next-gen data! Some of...AIRVF: a filtering toolbox for precise variant calling in Ion Torrent sequencing
By BioStar 2530 days agosourceforge.net - AIRVF that works on flowgram, raw and mapped reads and called variants to reduce artifact-driven false variant calls. Tests on sequencing data of standard reference material showed up to ∼98% reduction of false variants when combined to...ALPACA: A hybrid strategy for assembly of genomic DNA shotgun sequencing reads.
By Seema Singh 2401 days agogithub.com - ALPACA requires Celera Assembler 8.3 or later. It is recommended to build Celera Assembler from source. (Why? The pre-built binaries CA_8.3rc1 and CA8.3rc2 will work for any large data set. Detail paper...PureCN: copy number calling and SNV classification using targeted short read sequencing
By Jit 2300 days agobioconductor.org - This package estimates tumor purity, copy number, and loss of heterozygosity (LOH), and classifies single nucleotide variants (SNVs) by somatic status and clonality. PureCN is designed for targeted short read sequencing data, integrates well with...
