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www.well.ox.ac.uk - Platypus is a tool designed for efficient and accurate variant-detection in high-throughput sequencing data. By using local realignment of reads and local assembly it achieves both high sensitivity and high specificity. Platypus can detect...

NATIONAL JALMA INSTITUTE OF LEPROSY AND OTHER MYCOBACTERIAL DISEASES (INDIAN COUNCIL OF MEDICAL RESEARCH) P.O BOX 101, Dr. M. Miyazaki Marg, Tajganj, Agra - 282001 Applications are invited for a walk-in interview to be held in the Seminar...

Applications are invited for the position of Project Assistant in Bio-IT centre at IBAB, Electronic city, Bengaluru. The successful candidate will work in the next-generation sequencing (NGS) facility to perform nucleic acid isolations, quality and...

Gagneur lab at Gene Center, Ludwig-Maximilians-Universitaet, Munich, Germany Deadline for applications : January 15, 2014. Description : We seek a talented and motivated post-doc to develop computational methods for inferring the molecular...

github.com - ClinCNV detects CNVs in germline and somatic context in NGS data (targeted and whole-genome). We work in cohorts, so it makes sense to try ClinCNV if you have more than 10 samples (recommended amount - 40 since we estimate variances from...

Only bioinformatician can understand that multiplication and division are different but same thing :) Disclaimer: This cartoon is solely designed to create humour and fun, not to offend any computer experts.

csb5.github.io - LoFreq* (i.e. LoFreq version 2) is a fast and sensitive variant-caller for inferring SNVs and indels from next-generation sequencing data. It makes full use of base-call qualities and other sources of errors inherent in sequencing (e.g. mapping or...

Hidden Markov Models, the Viterbi Algorithm, and CpG Islands (in VB6) Problem : The CG island is a stretch of DNA (usually longer than 200 bases) in which the frequency of the CG sequence is higher than other regions. It is also called the CpG...

github.com - Key features Filters SNVs from any variant caller to remove false positives Calculates metrics based on BAM files and provides filtering not possible with other tools Fully user-configurable filtering (including which filters to use and their...

The main subject of interest in our laboratory is the study of the relationship among sequence, structure, and function in proteins and nucleic acids. Our research can be divided in two major topics: the study of the sequence-structure...