BOL

github.com - Simulated genomes with pre-defined and random genomic variants can be very useful for benchmarking genomic and bioinformatics analyses. Here we introduce simuG, a lightweight tool for simulating the full-spectrum of genomic variants (single...

Efflux pumps (RND family) Functioning of efflux systems in Gram-negative bacteria Determinants of the compound-efflux system interactions Action of inhibitors on efflux systems Structural and dynamical features of the efflux...

github.com - genome simulation across a population with zeta-distributed allele frequency, snps, insertions, deletions, and multi-nucleotide polymorphisms More at https://github.com/ekg/mutatrix ./mutatrix -S sample -P test/ -p 2 -n 10 reference.fasta

Broad area of research: Genome Annotation and Functional Genomics Bergman Lab is actively engaged in the development and application of computational methods to improve the annotation of functional biological features in genome sequences....

China’s BGI says it can sequence a genome for just $100

Creators of software widely used in computational biology discuss the factors that contributed to their success

In the Svardal lab they are interested how the astonishing natural diversity we see on earth came into being, by which forces it formed and how it is changing today. Hence, they are trying to understand the process of evolution, with mathematical...

Indian Statistical Institute Kolkata invites applications for the following posts 2013 Oct Advertisement from Indian Statistical Institute Post: Network Analysis No. of Positions: 01 Educational Qualifications: Candidate should have...

training.galaxyproject.org - The main challenge associated with non-diploid variant calling is the difficulty in distinguishing between the sequencing noise (abundant in all NGS platforms) and true low frequency variants. Some of the early attempts to do this well have been...

In our research, we combine computational methods with an experimental component in a unified effort to develop comprehensive descriptions of genetic systems of cellular controls, including those whose malfunctioning becomes the basis of genetic...