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Should you get sequenced? Not all bad genes predict disease
By Rahul Agarwal 4671 days agowww.today.com - “What we really don’t know yet is whether the predictive aspects of the genome are going to turn out to be beneficial or potentially harmful” “As we roll out genomic medicine we are fighting against this society-wide...Latest paper on comparison of mapping tools
By Rahul Agarwal 4666 days ago Comments (1)www.biomedcentral.com - A. Hatem, D. Bozdag, A. E. Toland, U. V. Catalyurek "Benchmarking short sequence mapping tools" BMC Bioinformatics, 14(1):184, 2013. http://bmi.osu.edu/hpc/software/benchmark/ http://bmi.osu.edu/hpc/software/pmap/pmap.html Other similiar...Largest Genome Sequenced
By Rahul Agarwal 4467 days agowww.news.ucdavis.edu - The enormous size of the loblolly pine genome having 22 billion base pairs compared to only 3 billion in the human genome. In other words, it is seven times larger than a human’s and also the largest and the most...New RNA Seq tool
By Rahul Agarwal 4432 days ago Comments (4)www.genengnews.com - "By removing the time-consuming step of read mapping, the authors reported, Sailfish able to provide quantification estimates 20–30 times faster than current methods without loss of accuracy." Tool...Genomics and sequencing approach for identification of biomarkers to assess the efficacy of TGF-βRI...
By Rahul Agarwal 4330 days agoLiver cancer is third leading cause of deaths and fourth most frequent occuring cancer worldwide. There are multiple signaling pathways responsible for causing cancer amongst which TGFb is most important cytokine whose signaling pathway promote...Scaffolding of a bacterial genome using MinION nanopore sequencing
By Rahul Agarwal 3994 days agowww.nature.com - Second generation sequencing has revolutionized genomic studies. However, most genomes contain repeated DNA elements that are longer than the read lengths achievable with typical sequencers, so the genomic order of several generated contigs cannot...simNGS and simLibrary – Software for Simulating Next-Gen Sequencing Data
By Jit 3119 days agowww.ebi.ac.uk - simNGS is software for simulating observations from Illumina sequencing machines using the statistical models behind the AYB base-calling software. By default, observations only incorporate noise due to sequencing and do not incorporate effects from...vt: a variant tool set that discovers short variants from Next Generation Sequencing data.
By Jit 2328 days agogenome.sph.umich.edu - vt is a variant tool set that discovers short variants from Next Generation Sequencing data. https://genome.sph.umich.edu/wiki/Vt https://github.com/atks/vtEntire Human Genome Sequencing !
By LEGE 802 days agoCost-effective whole human genome sequencing has revolutionized the landscape of genetic research and personalized medicine by making comprehensive genetic analysis accessible to a wider population. Through advancements in sequencing technologies,...
