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Trust But Verify: Sequencing Your Cell Lines Might Reveal an Uninvited Guest
By LEGE 276 days agoHigh-throughput sequencing has become indispensable in cell biology, enabling detailed insights into chromatin structure, gene expression, and regulatory dynamics. Yet, when faced with unexpectedly low mapping rates to the human genome,...CONTIGuator !
By BioStar 2346 days agosourceforge.net - CONTIGuator is a Python script for Linux environments whose purpose is to speed-up the bacterial genome assembly process and to obtain a first insight of the genome structure using the well-known artemis comparison tool (ACT).PureCN: copy number calling and SNV classification using targeted short read sequencing
By Jit 2767 days agobioconductor.org - This package estimates tumor purity, copy number, and loss of heterozygosity (LOH), and classifies single nucleotide variants (SNVs) by somatic status and clonality. PureCN is designed for targeted short read sequencing data, integrates well with...HaploMerger2: rebuilding both haploid sub-assemblies from high-heterozygosity diploid genome...
By BioStar 2718 days agogithub.com - HM2 can process any diploid assemblies, but it is especially suitable for diploid assemblies with high heterozygosity (≥3%), which can be difficult for other tools. This pipeline also implements flexible and sensitive assembly error detection, a...Tetra-Nucleotide Analysis
By Jit 3229 days agochunlab.wordpress.com - A tetra-nucleotide is a fragment of DNA sequence with 4 bases (e.g. AGTC or TTGG). Pride et al. (2003) showed that the frequency of tetra-nucleotides in bacterial genomes contain useful, albeit weak, phylogenetic signals. Even though...SocBiN Bioinformatics 2014
14th annual conference in Bioinformatics Date : June 10-13 Organizers: The Society for Bioinformatics in Northern European countries (SocBiN) and the Norwegian Bioinformatics Platform / ELIXIR.NO Venue: Department of Informatics,...GEnView: A phylogeny based comparative genomics software to analyze the genetic environment of genes
By Abhi 1530 days agogithub.com - A phylogeny based comparative genomics software to analyze the genetic environment of genes. The user can select one or several taxa and provide one or several reference protein(s). Genomes and plasmids (based on user choice) will be downloaded from...PyParanoid: a pipeline for rapid identification of homologous gene families in a set of genomes
By BioStar 2031 days agogithub.com - PyParanoid is a pipeline for rapid identification of homologous gene families in a set of genomes - a central task of any comparative genomics analysis. The "gold standard" for identifying homologs is to use reciprocal best hits (RBHs) which depends...Bioinformatics approach to Boar Taint
By Rahul Agarwal 4615 days ago Comments (3)Meat products obtained from intact male pigs often produce offensive smell or odour which is recognized as a complex genetic trait called boar taint.Androstenone and Skatole in the fat primarily cause boar taint. Metabolism of androstenone and...A-allele of SLC24A5 gene is found to be responsible for variation in skin color of South-East...
By Rahul Agarwal 4497 days agoMore is the A -allele, More is fairer the Skin !!
