Best practices in bioinformatics training for life scientists
Among life scientists, from clinicians to environmental researchers, a common theme is the need not just to use, and...resources but also to understand their underlying fundamental theoretical and practi...3969 days ago
Following the scientific literature: A personal practical guide for young computational biologists
The goal of this guide is to describe why, when, where and how can you follow the most up-to-date science of interest and what p...3960 days ago
1155 days ago
CNIDARIA: fast, reference-free phylogenomic clustering
Motivation: Identification of biological specimens is a major requirement for a range of applications. Reference-free...nd arbitrarily large phylogenetic distances. Results: We present Cnidaria, a practi...2931 days ago
Statistical for biological research
There is no disputing the importance of statistical analysis in biological research, but too often it is considered o...important statistical issues that biologists should be aware of and provides practi...2792 days ago
2639 days ago
AVID: A Global Alignment Program
A new global alignment method called AVID. The method is designed to be fast, memory efficient, and practi...2590 days ago
Meraculous: De Novo Genome Assembly with Short Paired-End Reads
We describe a new algorithm, meraculous, for whole genome assembly of deep paired-end short reads, and apply it to th...kbp, and many gaps between contigs can be closed using paired-end placements. Practi...2423 days ago
Multi-CAR: a tool of contig scaffolding using multiple references
we design a simple heuristic method to further revise our single reference-based scaffolding tool CAR into a new one...erences to more accurately order and orient the contigs of a draft genome. In practi...2303 days ago
STELLAR: fast and exact local alignments
STELLAR is very practical and fast on very long sequences which makes it a suitable new tool for finding local alignments between genomic sequences under the edit distance model. Binaries are freely available for Linux, Windows, and Mac OS X at http://www.seqan.de/projects/stellar.2127 days ago