Tools to detect synteny blocks regions among multiple genomes
The synteny block (which etymologically means “on the same ribbon”) is a collection of contiguous genes located on the same chromosome. These block regions have mo...2608 days ago
Dynamic chromosome breakpoints !!!
Cell division involves the distribution of identical genetic material, DNA, to two daughters’ cells. During this process, duplicated deoxyribonucleic acid (DNA) goes thr...3551 days ago
Structural variation: the hidden genomic treasure
Genome re-sequencing projects have revealed substantial amounts of genetic variation between individuals extending beyond single nucleotide polymorphisms (SNPs) and short inde...2701 days ago
Software and Tools to detect structure variation with long reads !!
Uncovering the connection between genetics and heritable diseases requires an approach that looks at all the variant bases and types in a genome. While a PacBio de novo&n...2606 days ago
List of GOI approved peer reviewed bioinformatics and computational biology journals
Unfortunately, we now live in a world where the integrity of peer-reviewed journals is being threatened by the rise of the academic version of fake news – something many...2565 days ago
List of Research Institutes in India (Biological Sciences/ Biotechnology)
A laboratory (normally lab) is a facility that provides controlled conditions in which scientific or technological research, experiments, and measurement may be performed. Th...2362 days ago
List of motif discovery tools !
In genetics, a sequence motif is a nucleotide or amino-acid sequence pattern that is widespread and has, or is conjectured to have, a biological significance. For proteins,...1991 days ago
Understanding reads mapping and flags !
Linear Alignment: An alignment of a read to a single reference sequence that may include insertions, deletions, skips and clipping, but may not include directio...1835 days ago
Bioinformatics tools for telomere to telomere assembly !
● Merfin – k-mer-based assembly and variant calling evaluation for improved consensus accuracy (Arang Rhie)● PanGenie – algorithm that leverage...990 days ago
Protocol for De novo Genome Assembly using Illumina Reads
In this protocol, we address and describe the de novo assembly method for small to medium-sized genomes. What is de novo genome assembly?The method of taking a large number o...1203 days ago