RosettaAntibodyDesign (RAbD): A general framework for computational antibody design
RosettaAntibodyDesign (RAbD) is a generalized framework for the design of antibod...lysis and rooted very much on our recent clustering of antibody CDR regions. It uses the North/Dunbr...1337 days ago
1300 days ago
URMAP, an ultra-fast read mapper
URMAP, a new read mapping algorithm. URMAP is an order of magnitude faster than BWA wi...r. However, GIAB reference variants are shown to be biased against repetitive regions which are difficult to map an...1297 days ago
MAGIC: A tool for predicting transcription factors and cofactors driving gene sets using ENCODE data
The algorithm presented herein, Mining Algorithm for GenetIc Contr...k for statistical enrichment of TFs and cofactors in gene bodies and flanking regions in gene lists without an ...1270 days ago
gggenomes: A grammar of graphics for comparative genomics
gggenomes is a versatile graphics package for comparative genomics. It extends the popular R visualization packageggplot2 by adding dedicated plot functions for genes, syntenic regions, etc. and verbs to manipulate the plot to, for example, quickly zoom in into gene neighborhoods.1203 days ago
1176 days ago
odgi: optimized dynamic genome/graph implementation
odgi provides an efficient and succinct dynamic DNA sequence graph model, as well...ing. The RAM and computational savings are substantial. In partially ordered regions of the graph, most deltas wil...837 days ago
816 days ago
The complete sequence of a human genome
The completed regions include all centromeric satellite arrays, recent segmental duplications, and the short arms of all five acrocentric chromosomes, unlocking these complex regions of the genome to variational and functional studies.779 days ago
421 days ago