2939 days ago
Assembly and diploid architecture of an individual human genome via single-molecule technologies
The research work shows that it is now possible to integrate single-molecule and high-throughput sequence data to generate de novo assembled genomes that approach refe...3221 days ago
Directional dominance on stature and cognition in diverse human populations
Analysis of the genomes of >350,000 individuals revealed the existence of a small t...vidence that increased stature and cognitive function have been positively selected in human...3221 days ago
Resolving the complexity of the human genome using single-molecule sequencing
The human genome is arguably the most complete mammalian reference assembly yet more than 16...s-single-molecule-sequencing-close-gaps-chart-complexity-human-reference suggest a greater complexity of the human...3221 days ago
Simons Genome Diversity Project
Complete genome sequences from more than one hundred diverse human populations All genomes in the dataset were seq...enetic analysis. The researchers eliminated bias of alleles toward matching the human...1093 days ago
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2938 days ago
MEDEA: Comparative Genomic Visualization with Adobe Flash
As the number of sequence and annotated genomes grows larger, the need to understand, compare, and contrast the data becomes increasingly important. Using the power of the human...2931 days ago
PolyPhen-2: Prediction of functional effects of human nsSNPs
PolyPhen-2 (Polymorphism Phenotyping v2) is a tool which predicts possible impact of an amino acid substitution on the structure and function of a human protein using straightforward physical and comparative considerations.2905 days ago