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  • CheckM:Assessing the quality of microbial genomes recovered from isolates, single cells, and...

CheckM:Assessing the quality of microbial genomes recovered from isolates, single cells, and metagenomes

http://ecogenomics.github.io/CheckM/

CheckM provides a set of tools for assessing the quality of genomes recovered from isolates, single cells, or metagenomes. It provides robust estimates of genome completeness and contamination by using collocated sets of genes that are ubiquitous and single-copy within a phylogenetic lineage. Assessment of genome quality can also be examined using plots depicting key genomic characteristics (e.g., GC, coding density) which highlight sequences outside the expected distributions of a typical genome. CheckM also provides tools for identifying genome bins that are likely candidates for merging based on marker set compatibility, similarity in genomic characteristics, and proximity within a reference genome tree.