BioStar
Bioinformatician
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ALLHiC: Phasing and scaffolding polyploid genomes based on Hi-C data
By BioStar 2165 days ago
https://github.com/tangerzhang/ALLHiC/wiki
The major problem of scaffolding polyploid genome is that Hi-C signals are frequently detected between allelic haplotypes and any existing stat of art Hi-C scaffolding program links the allelic haplotypes together. To solve the problem, we developed a new Hi-C scaffolding pipeline, called ALLHIC, specifically tailored to the polyploid genomes. ALLHIC pipeline contains a total of 5 steps: prune, partition, rescue, optimize and build.
