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UTGB (University of Tokyo Genome Browser) Toolkit is an open-source software for developing personalized genome browsers that work in web browsers.
Thanks for the list of good genome browsers. But if someone is looking to do some sort of coding/programming stuff and implement/add in any pipeline then GBrowse is there for the rescue. GBrowse is a combination of database and interactive web pages for manipulating and displaying annotations on genomes.
Find more at GBrowse wiki page http://gmod.org/wiki/GBrowse
As a bioinfomatician we need a good software to manage the huge amout of omics data. Here is one open source software for omics data managements.
Link @ https://arvados.org/
High-throughput experimental technologies are generating increasingly massive and complex genomic data sets. The sheer enormity and heterogeneity of these data threaten to make the arising problems computationally infeasible. Fortunately, powerful algorithmic techniques lead to software that can answer important biomedical questions in practice.
Check out this review for more detail of computational solution of huge omics data: http://www.nature.com/nrg/journal/v14/n5/full/nrg3433.html#!
Compressive Genomics is the solution deal with problem arisen due to sudden explosion of redundant data generated by current sequencing technology and other solution is 3rd and 4th generation sequencing machines which are based on sequencing single molecule and tend to produce long reads with less redundant data.