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PureCN: copy number calling and SNV classification using targeted short read sequencing
By Jit 2770 days agobioconductor.org - This package estimates tumor purity, copy number, and loss of heterozygosity (LOH), and classifies single nucleotide variants (SNVs) by somatic status and clonality. PureCN is designed for targeted short read sequencing data, integrates well with...GIGGLE: a search engine for large-scale integrated genome analysis
By Jit 2981 days agogithub.com - GIGGLE is a genomics search engine that identifies and ranks the significance of genomic loci shared between query features and thousands of genome interval files. GIGGLE (https://github.com/ryanlayer/giggle) scales to billions of intervals and is...sourmash: Quickly search, compare, and analyze genomic and metagenomic data sets.
By BioStar 612 days agogithub.com - sourmash is a k-mer analysis multitool, and we aim to provide stable, robust programmatic and command-line APIs for a variety of sequence comparisons. Some of our special sauce includes: FracMinHash sketching, which enables accurate...
Is reference genome necessary for gene expression study in transcriptome sequencing or for variant discovery in genome sequencing?
Rahul Agarwal 4619 days ago320000 viruses in mammals yet to sequenced in future!!!
By Rahul Agarwal 4571 days ago70 per cent of emerging viral diseases such as HIV/AIDS, West Nile, Ebola, SARS, and influenza, are zoonoses - infections of animals that cross into humans.RNA Bioinformatics and High Throughput Analysis Jena
Research Topics: High Throughput Sequencing Analysis Comparative Genomics Identification and Annotation of Non-coding RNAs Bioinformatic Analysis and System Biology of Viruses Coevolution of Proteins and RNAs Algorithmic...Bio-Rad Acquires GnuBIO
By Rahul Agarwal 4343 days agoGnuBIO-Developer of Droplet-Based DNA Sequencing TechnologyDeadly Human Pathogen Cryptococcus Sequenced
By Rahul Agarwal 4337 days agoCryptococcus neoformans is a fungus responsible for a million cases of pneumonia and meningitis every year- are so malleable and dangerous
