Merfin: improved variant filtering, assembly evaluation and polishing via k-mer validation
...d consensus accuracy and reduced frameshift errors when applied to human and nonhuman assemblies built from Pacific Biosciences HiFi and continuous long reads or Oxford Nanopore read...821 days ago
HairSplitter: assembling long reads in an unknown number of haplotypes
Pros and cons of HairSplitter Limitations of HairSplitter: Not very fast: it re-polishes the whole assembly Limited in the number of haplotypes Strengths of H...574 days ago
Metabuli 분리 improves metagenomic read classification
...to enable both specific and sensitive characterization of metagenomic samples. In addition, it can classify reads against a database of any size as long as it fits in the hard disk....395 days ago
CLAW: Chloroplast Long-read Assembly Workflow
CLAW (Chloroplast Long-read Assembly Workflow) is an mostly-automated Snakemake-based workflow for the assembly of chloroplast genomes. CLAW uses chloroplast long-reads, which are baited out o...132 days ago
UniAligner: a parameter-free framework for fast sequence alignment
...nt approaches, such as the Smith-Waterman algorithm, that work well for most sequences, fail to construct biologically adequate alignments of extra-long tandem repeats (ETRs), such a...116 days ago
Severus: a somatic structural variation (SV) caller for long reads
Severus is a somatic structural variation (SV) caller for long reads (both PacBio and ONT). It is designed...rate and complete somatic and germline calls. Severus takes advantage of long-read phasing and uses the bre...94 days ago
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