Dynamic chromosome breakpoints !!!
Cell division involves the distribution of identical genetic material, DNA, to two daughters’ cells. During this process, duplicated deoxyribonucleic acid (DNA) goes throu...3588 days ago
Structural variation: the hidden genomic treasure
Genome re-sequencing projects have revealed substantial amounts of genetic variation between individuals extending beyond single nucleotide polymorphisms (SNPs) and short indels...2739 days ago
Software developed in pevsner lab
DRAGON: Database Referencing of Array Genes Online SNOMAD: Standardization and Normalization of Microarray Data SNPduo: SNP Analysis Between Two Individuals S...3535 days ago
RACA: Reference-Assisted Chromosome Assembly
Rreference-Assisted Chromosome Assembly (RACA), an algorithm to reliably order and orient sequence scaffolds generated by NGS and assemblers into longer chromosomal fragments us...2987 days ago
Genome Assembly Tools and Software - PART2 !!
The genome assemblers generally take a file of short sequence reads and a file of quality-value as the input. Since the quality-value file for the high throughput short reads is...2722 days ago
Apps for Busy Bioinformatics Researchers !!!
DNAApp: DNAApp: for iPhone/iPad This is an iOS app that allows for the opening and analysis of DNA sequencing files - ab1. It includes handy tools such as "Reverse Complement"...3577 days ago
Tools for Searching Repeats And Palindromic Sequences
What are genomic interspersed repeats? In the mid 1960's scientists discovered that many genomes contain stretches of highly repetitive DNA sequences ( see Reassociation Kineti...2247 days ago
Breaking chromosomes to study cancer !!!
Chromosomes are present in every cell of our body and they contain the information the body needs to develop and function properly. This information is carried in genes that are...3615 days ago
2238 days ago
Post-doctoral Research Assistant in Genetics
Post-doctoral Research Assistant in Genetics Camden, North London £31.1K per annum inclusive of London Weighting This is a fixed term post for 36 months. We wish to recr...3658 days ago
Postdoctoral Research Assistant at RVC
This is a fixed term post for 24 months. We wish to recruit a highly motivated, postdoctoral scientist to carry out a BBSRC funded project in the laboratory of Dr. Denis Lark...2163 days ago
3888 days ago
How DNA is Packaged (Advanced)
Each chromosome consists of one continuous thread-like molecule of DNA coiled tightly around proteins, and contains a portion of the 6,400,000,000 basepairs (DNA building blocks...3912 days ago
Comment on "Tools to detect synteny blocks regions among multiple genomes"
Thanks for such an informative blog. I notice MCScan is missing. MCScan is an algorithm able to scan multiple genomes or subgenomes in order to identify putative homologous chromosomal regions, and align these regions using genes as anchors. More at http://www.ncbi.nlm.nih.gov/pubmed/222176003709 days ago