Tools to detect synteny blocks regions among multiple genomes
...here have been various algorithms developed to identify the conserved homologous synteny blocks (HSB) amongst...species. It is intended to help scientists study and analyze synteny, homologous genes and other conserved ele...2638 days ago
Structural variation: the hidden genomic treasure
...nerated by several different mechanisms including non‐allelic homologous recombination, non‐homologous end‐joining and deoxyribonucl...ariants can arise by several mechanisms, including nonallelic homologous recombination (NAHR), nonhomo...2730 days ago
PhyloGrapher - Graph Visualization Tool
PhyloGrapher is a program designed to visualize and study evolutionary relationships within families of homologous genes or proteins (elements).PhyloGrapher is a drawing tool...2978 days ago
Comparative genomics educational material and papers bookmarks
Alignment of the porcine genome against seven other mammalian genomes (Supplementary Information) identified homologous synteny blocks (HSBs). Using porcine HSBs and stringent filtering...2761 days ago
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List of In-silico Binding Site Prediction Tools
...e. If a sequence is submitted then Phyre is run to predict the structure. The structure is then ussed to search a structural library to identify homologous structures with bound ligands...3771 days ago
Breaking chromosomes to study cancer !!!
...osomal translocations occur following double-strand breaks (DSBs) in DNA when a section of one chromosome is exchanged with that of another, non-homologous chromosome. These exchanges m...3607 days ago
Illumina to Acquire Pacific Biosciences for Approximately $1.2 Billion !
...ng platforms address the majority of sequencing applications optimally, select applications, such as de novo sequencing and sequencing of highly homologous regions of genomes, are bette...2038 days ago
Bioinformatics -- Understanding of living systems through information science
...ngements, such as inversions, transpositions, and duplications, occur. The genome comparison system developed by the Sakakibara Lab calculates homologous sequences called anchors, whi...3944 days ago
Comment on "Tools to detect synteny blocks regions among multiple genomes"
...gous genes: Identify the orthologous genes between the genomes using tools such as OrthoFinder or OrthoMCL. Orthologous genes are genes that are homologous and have a common ancestor, b...451 days ago
Comment on "Tools to detect synteny blocks regions among multiple genomes"
Thanks for such an informative blog. I notice MCScan is missing. MCScan is an algorithm able to scan multiple genomes or subgenomes in order to identify putative homologous chromosomal regions, and align these regions using genes as anchors. More at http://www.ncbi.nlm.nih.gov/pubmed/222176003701 days ago