18 days ago
Dynamic chromosome breakpoints !!!
...nd sealing of the resulting recombined molecules happens. The “chromosomal breakpoints” refers to...965/). These breakage may lead to genetic diseases or participate to chromosomal rearranmgnets and contributed...3560 days ago
Structural variation: the hidden genomic treasure
...t on genome evolution and should not be neglected when studying the genetics of adaptation and speciation. SVs were classically defined as chromosomal rearrangements larger than 1k...2710 days ago
Software developed in pevsner lab
...a pediSNP: Analyze SNP Data From a Pedigree of Two Generations kcoeff: Calculate Cotterman Coefficients of SNP Genotype Data triPOD: Detects chromosomal abnormalities in parent-child...3507 days ago
RACA: Reference-Assisted Chromosome Assembly
...e-Assisted Chromosome Assembly (RACA), an algorithm to reliably order and orient sequence scaffolds generated by NGS and assemblers into longer chromosomal fragments using comparative g...2959 days ago
Genome Assembly Tools and Software - PART2 !!
...sisted Chromosome AssemblyRACA is an algorithm to reliably order and orient sequence scaffolds generated by NGS and assemblers into longer chromosomal fragments using comparative g...2693 days ago
Apps for Busy Bioinformatics Researchers !!!
...ger/id637353801?mt=8 YeastGenome: iPhone/iPad Use YeastGenome to quickly find fundamental information about Saccharomyces cerevisae genes and chromosomal features. Search gene names,...3549 days ago
Tools for Searching Repeats And Palindromic Sequences
...striction endobucleases) designed to cut the DNA strands at specific locations (i.e., at palindromes). Palindromes may arise from brakeage and chromosomal inversions that form inverted...2219 days ago
Breaking chromosomes to study cancer !!!
...has a reciprocal translocation. Reciprocal chromosomal translocations occur followin...ns seen in leukemia and childhood sarcomas. Chromosomal translocations have been well...allow for the clarification of how and why chromosomal translocation occurs, which w...3587 days ago
2210 days ago
Post-doctoral Research Assistant in Genetics
...es and existing algorithms. The post holder will use cutting edge computational and laboratory approaches to generate chromosomal assemblies for sequenced genomes, study chromosomal structures and genome differe...3630 days ago
Postdoctoral Research Assistant at RVC
...ad Sci USA. 2013. 110 (5)). The post holder will use cutting edge computational and laboratory approaches to generate chromosomal assemblies for sequenced genomes, study chromosomal structures and differences be...2135 days ago
3860 days ago
How DNA is Packaged (Advanced)
...omes known as chromatin. This structure, is then looped and further packaged using other proteins (which are not shown here) to give the final "chromosomal" shapes. It is this remarkabl...3884 days ago
Comment on "Tools to detect synteny blocks regions among multiple genomes"
Thanks for such an informative blog. I notice MCScan is missing. MCScan is an algorithm able to scan multiple genomes or subgenomes in order to identify putative homologous chromosomal regions, and align these regions using genes as anchors. More at http://www.ncbi.nlm.nih.gov/pubmed/222176003681 days ago