2936 days ago
InfoGenomeR: Integrative reconstruction of cancer genome karyotypes
InfoGenomeR is the Integrative Framework for Genome Reconstruction that uses a breakpoint graph...connectivity among genomic segments at the genome-wide scale. InfoGenomeR integ...ptimal breakpoint graph representing cancer genomes. More at https://www...1093 days ago
3231 days ago
Scaffolding of a bacterial genome using MinION nanopore sequencing
Second generation sequencing has revolutionized genomic studies. However, most genomes contain repeated DNA element...3222 days ago
Assembly and diploid architecture of an individual human genome via single-molecule technologies
The research work shows that it is now possible to integrate single-mol...e and high-throughput sequence data to generate de novo assembled genomes that approach reference quality. https://www.genomeweb.com/sequencing-technology/...3218 days ago
Directional dominance on stature and cognition in diverse human populations
Analysis of the genomes of >350,000 individuals revealed&nb...ce of a small though measureable association between genome-wide homozygosi...cognitive function have been positively selected in human evolution, whereas many import...3218 days ago
Resolving the complexity of the human genome using single-molecule sequencing
The human genome is arguably the most complete mammalian reference assembly yet more than 160...ults in this paper https://www.genomeweb.com/sequencing/team-uses-sing...ng-close-gaps-chart-complexity-human-reference suggest a greater complexity of the human genome in the form of variation of l...3218 days ago
1089 days ago
Simons Genome Diversity Project
Complete genome sequences from more than one hundred diverse human populations All genomes in the dataset were sequenced to at least 30x coverage...rchers eliminated bias of alleles toward matching the human genome reference sequence, and determined g...1089 days ago
Alignment of closely related whole genomes/scaffolds
With the relative ease and low cost of current...increase in the number of sequenced genomes for species across the tree...t can quickly compare multiple whole-genome sequences, millions of base p...reated to report new tools for whole genome alignments. Please report ne...3016 days ago