Software and Tools to detect structure variation with long reads !!
...most novel SV variants. 8-10X PacBio coverage of single genomes or trios reveals triple the SVs detectable by short-read data. With Single Molecule, Real-Time (SMRT) Sequencing,...2608 days ago
DNA testing companies around the globe !
It was realized in the 1940s that DNA molecules are passed down through the generations of a family. In 1953 Watson and Crick elucidated the chemical structure of this molecule as a twisted ladder (a &lsquo...2487 days ago
Assembly and diploid architecture of an individual human genome via single-molecule technologies
The research work shows that it is now possible to integrate single-molecule and high-throughput sequence dat...s://www.genomeweb.com/sequencing-technology/researchers-combine-single-molecule-sequencing-mapping-technologi...3220 days ago
Resolving the complexity of the human genome using single-molecule sequencing
...ariation remain poorly understood ten years after its completion. The results in this paper https://www.genomeweb.com/sequencing/team-uses-single-molecule-sequencing-close-gaps-chart-c...3220 days ago
India's own first drug - from Biocon.
...oduction of new skin cells. More at >> Biocon, India's largest publicly-held biotechnology firm, launched its second novel 'lab-to-market' molecule, Alzumab, to treat chronic pl...3920 days ago
Bio++ : C Language libraries for your biological need
...42.Dutheil J, Galtier N. Detecting groups of coevolving positions in a molecule: a clustering approach. BMC E...tier N. A model-based approach for detecting coevolving positions in a molecule. Mol Biol Evol. 2005 Sep;22(9...3947 days ago
List of In-silico Binding Site Prediction Tools
...ction of the effect of modifications to small molecules that bind to the active and/...ot only for understanding the function of the molecule in detail but also for struct...problem. Here we introduce ConCavity, a small molecule binding site prediction algor...3744 days ago
Tools for Searching Repeats And Palindromic Sequences
...NA are termed the 5' (phosphate bound to the 5' position carbon) and 3' (phosphate bound to the 3' carbon) ends to indicate a polarity within the molecule. Using the letters A, T, C, G...2211 days ago
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SCFBio have developed Sanjeevini
...terface. The app now supports all major small molecule file formats (pdb, mol, sdf,...rs Checks Lipinski's rule of five for ligand molecule 11 Molecular volume Ca...TPACM4 Partial charge calculator for small molecules 18 Wiener index Wiene...2361 days ago
SRF/JRF/RA @ UNIVERSITY OF HYDERABAD
...CSIR- sponsored research project. JRF/SRF/RA (one vacancy) CSIR sponsored “In silico design, identification and in vitro validation of lead molecule inhibitors to Bcr-Abl kinase”...3856 days ago
Walk-ins for JRF ans SRF post in NIRRH, Mumbai
Title of project- "EXPLORING THE HINGE AND TRANSMEMBRANE REGION OF HUMAN FSHR FOR DESIGN OF SMALL MOLECULE AND PEPTIDOMIMETIC MODULATORS" Name of the Post- Junior Research Fellow No....3264 days ago
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The Story of You: ENCODE and the human genome
...lled Mendel started breeding pea plants we've been learning about our genomes. In 1953, Watson, Crick and Franklin described the structure of the molecule that makes up our genomes: th...3906 days ago
How DNA is Packaged (Advanced)
Each chromosome consists of one continuous thread-like molecule of DNA coiled tightly around proteins, and co...formed when eight separate histone protein subunits attach to the DNA molecule. The combined tight loop of D...3876 days ago
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Single molecule Sequencing (SMS)
SMS is now slowly gaining place in sequencing world, more and more scientists now keen to use SMS method to sequence molecules in comparatively less complex protocal and less time. One...3227 days ago
INC-Seq: accurate single molecule reads using nanopore sequencing
INC-Seq reads enabled accurate species-level classification, identification of species at 0.1 % abundance and robust quantification of relative abundances, providing a cheap and effective approach for pathogen detection and microbiome profiling on the MinION system.Tags: INC-Seq, accurate, single, molecule, reads, nopore, sequencing
2351 days ago
Flye: Fast and accurate de novo assembler for single molecule sequencing reads
Flye is a de novo assembler for long and noisy reads, such as those produced by PacBio and Oxford Nanopore Technologies. The algorithm uses an A-Bruijn graph to find the overlaps between reads and does not require them to be error-corrected. After the initial assembly, Flye performs an extra repe...Tags: Flye, de novo, assembler, ONT, Nanopore, PacBio, Assembly, single, molecule, sequencing, reads
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Comment on "Want to Know which genome assembler rule the world ?"
Canu Assembler is my personal favourate.Canu is a fork of the Celera Assembler, designed for high-noise single-molecule sequencing (such as the PacBio RS II/Sequelor Oxford Nanopore MinION).1950 days ago
Comment on "List of popular bioinformatics software/tools"
Mapping single molecule sequencing reads using Basic Local Alignment with Successive Refinement (BLASR) http://bix.ucsd.edu/projects/blasr/3010 days ago