BOL

sourceforge.net - Quality assessment of this mRNA Transcript Assembly Software is described in EvidentialGene_quality. Too many transcript assemblies is much better than too few. It allows one then to apply biological criteria to pick out the best ones. Don't...

Integrated solutions CLCbio Genomics Workbench - de novo and reference assembly of Sanger, Roche FLX, Illumina, Helicos, and SOLiD data. Commercial next-gen-seq software that extends the CLCbio Main Workbench software. Includes SNP detection,...

List of generic simulation software/tools/resource with brief description and homepage ALF A Simulation Framework for Genome Evolution http://www.cbrg.ethz.ch/alfBayesian Serial SimCoal Bayesian Serial SimCoal, (BayeSSC) is a modification of...

Package suites gather software packages and installation tools for specific languages or platforms. We have some for bioinformatics software.

List of bioinformatics tools/Software Website References for genome assembly:

The genome assemblers generally take a file of short sequence reads and a file of quality-value as the input. Since the quality-value file for the high throughput short reads is usually highly memory-intensive, only a few assemblers, best suited for...

shendurelab.github.io - LACHESIS is method that exploits contact probability map data (e.g. from Hi-C) for chromosome-scale de novo genome assembly. Further information about LACHESIS, including source code, documentation and a user's guide are available...

pevsnerlab.kennedykrieger.org - DRAGON: Database Referencing of Array Genes Online SNOMAD: Standardization and Normalization of Microarray Data SNPduo: SNP Analysis Between Two Individuals SNPtrio: Analyzing and Visualizing and Inheritance Patterns in Trios SNPscan: Data...

Ligand docking referred to cases where small molecule (“ligand”) is being docked into much larger macromolecule ("target"). The following is partial list of docking software, focusing on free (at least for academic institutes) and/or...

broadinstitute.github.io - Picard is a set of command line tools for manipulating high-throughput sequencing (HTS) data and formats such as SAM/BAM/CRAM and VCF. These file formats are defined in the Hts-specs repository. See especially the SAM specification and the VCF...