Evolution of the adaptive immune system Marsupial and monotreme immune genes MHC Diversity and Conservation Marsupial and monotreme genomics Comparative Genomics Genetics of Tasmanian Devil facial tumour disease
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We focus on fundamental questions in genomics, ecology, and evolution. Our methods include fieldwork and labwork, but most of our time is spent analyzing genomics data using computational biology approaches.
Ant / bacteria co-evolution, landscape...
The goal of our research is to interpret and distill this complexity through accurate analysis and modeling of molecular pathways, particularly those in which malfunctions lead to the manifestation of disease. We are inventing integrative methods...
Companies and governments do research and development (R&D/ R'n'D/ R+D) to promote innovation in order to produce new goods or services and/or enhance existing product lines. R&D covers all actions inside an organization aimed at boosting...
github.com - find the resources we provide here useful in getting you set up to analyse and interpret your data.
To reference VESPA: https://peerj.com/preprints/1895/
Documentation is now hosted on ReadTheDocs
omega.omicsbio.org - Omega found overlaps between reads using a prefix/suffix hash table. The overlap graph of reads was simplified by removing transitive edges and trimming short branches. Unitigs were generated based on minimum cost flow analysis of the overlap graph...
github.com - Miniasm is a very fast OLC-based de novo assembler for noisy long reads. It takes all-vs-all read self-mappings (typically by minimap) as input and outputs an assembly graph in the GFA format. Different from mainstream...
github.com - MashMap is a fast and approximate software for mapping long reads (PacBio/ONT) or assembly to reference genome(s). It maps a query sequence against a reference region if and only if its estimated alignment identity is above a specified threshold. It...
www.ncbi.nlm.nih.gov - RGFA, an implementation of the proposed GFA specification in Ruby. It allows the user to conveniently parse, edit and write GFA files. Complex operations such as the separation of the implicit instances of repeats and the merging of linear paths can...