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By Rahul Nayak 2396 days agoList of popular bioinformatics educational resourcesFree resources to learn statistics
By BioStar 141 days agoonline.stat.psu.edu - Welcome to the course notes for STAT 414: Introduction to Probability Theory. These notes are designed and developed by Penn State's Department of Statistics and offered as open educational resources. These notes are free to use under...RNA Sequencing Helps Identify Functional Variants from GWAS
By Andaleeb 4020 days agoschizophreniaforum.org - For Alzheimer’s and other complex disorders, mining the genome for disease-associated variants is no longer the obstacle. The challenge nowadays is figuring out how the identified loci relate to disease. As reported last month in Nature and...Hoffman Lab
They develop machine learning techniques to better understand chromatin biology. These models and algorithms transform high-dimensional functional genomics data into interpretable patterns and lead to new biological...iSeqQC: a tool for expression-based quality control in RNA sequencing
By BioStar 1743 days agogithub.com - iSeqQC, an expression-based QC tool that detects outliers either produced due to variable laboratory conditions or due to dissimilarity within a phenotypic group. iSeqQC implements various statistical approaches including unsupervised clustering,...Tools for RNA classification
By Abhi 747 days ago Comments (1)The method used to isolate, enrich and sequence a sample will affect the composition of the sequencing data in terms of the types of RNA species represented and their relative abundancesS-plot2: Rapid Visual and Statistical Analysis of Genomic Sequences
By Abhimanyu Singh 2245 days agobitbucket.org - S-plot2 creates an interactive, two-dimensional heatmap capturing the similarities and dissimilarities in nucleotide usage between genomic sequences (partial or complete). In S-plot2, whole eukaryotic chromosomes and smaller prokaryotic genomes can...pbalign: maps PacBio reads to reference sequences and saves alignments to a BAM file
By Jit 2376 days agogithub.com - pbalign aligns PacBio reads to reference sequences, filters aligned reads according to user-specific filtering criteria, and converts the output to either the SAM format or PacBio Compare HDF5 (e.g., .cmp.h5) format. The output Compare HDF5 file...COSINE: non-seeding method for mapping long noisy sequences
By Jit 2222 days agogithub.com - Third generation sequencing (TGS) are highly promising technologies but the long and noisy reads from TGS are difficult to align using existing algorithms. Here, we present COSINE, a conceptually new method designed specifically for aligning long...
