834 days ago
The complete sequence of a human genome
The completed regions include all centromeric satellite arrays, recent segmental duplications, and the short arms of all five acrocentric chromosomes, unlocking these complex regions of the genome to variational and functional studies.827 days ago
Merfin: improved variant filtering, assembly evaluation and polishing via k-mer validation
Merfin, a k-mer based variant-filtering algorithm for improved accuracy in genotyp...ased on the expected k-mer multiplicity in the reads, independently of the quality...t from Pacific Biosciences HiFi and continuous long reads o...824 days ago
PuffAligner: a fast, efficient and accurate aligner based on the Pufferfish index
PuffAligner, a fast, accurate and versatile aligner built on top of the Pufferfish index. PuffAligner is able to p...PuffAligner requires considerably less memory to construct its index and align reads....806 days ago
Choosing the Right NGS Sequencing Instrument for Your Study
The right sequencing instrument for your study depends on your project goal. Setting aside turnaround time and price, it essentially comes down to the numbers of reads a...752 days ago
HairSplitter: assembling long reads in an unknown number of haplotypes
Pros and cons of HairSplitter Limitations of HairSplitter: Not very fast: it re-polish...istinguish repeated elements Only needs sequencing reads, potentially error-prone Hai...istinguish repeated elements Only needs sequencing reads,...577 days ago
536 days ago
Proksee: in-depth characterization and visualization of bacterial genomes
Proksee is an expert system for genome assembly, annotation and visualization. To begin using Proksee, provide a complete genome sequence, sequencing reads or a CGView/Proksee map JSON file.423 days ago
Metabuli 분리 improves metagenomic read classification
Metabuli 분리 improves metagenomic read classification through metamers, DNA-AA k-mers, to be sensitive and specific...ensitive characterization of metagenomic samples. In addition, it can classify reads a...398 days ago
MitoHiFi: a python pipeline for mitochondrial genome assembly from PacBio high fidelity reads
MitoHiFi v3.2 is a python pipeline distributed under MIT License ! MitoHiFi was first developed to assemble the mitogenomes for a wide range of species in the Darwin Tree of Life Project (DToL) https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-023-05385-y304 days ago