CoLoRMap: Correcting Long Reads by Mapping short reads
...mising way to address this issue. However, so far long reads are characterized by a high error rate, and assembling from long reads require a high depth of coverage. This motivates t...2099 days ago
1946 days ago
mosdepth: fast BAM/CRAM depth calculation for WGS, exome, or targeted sequencing
mosdepth can output: per-base depth about 2x as fast samtools depth--about 25 minutes of CPU time for a 30X genome.mean per-window depth given a window size--as would...at the given thresholds.A summary of mean depths per chromosome and within sp...1646 days ago
Minipolish: A tool for Racon polishing of miniasm assemblies
...sembly, while keeping the assembly in graph form. It also takes care of some of the other nuances of polishing a miniasm assembly: Adding read depth information to contigs Fixin...1629 days ago
SeQuiLa-cov: A fast and scalable library for depth of coverage calculations
...as well as test data are publicly accessible at the project documentation site http://biodatageeks.org/sequila/benchmarking/benchmarking.html#depth-of-coverage. An archival copy...1617 days ago
ClinCNV: Detection of copy number changes in Germline/Trio/Somatic contexts in NGS data
...nt - 40 since we estimate variances from the data). By "cohort" we mean samples sequenced with the same enrichment kit with approximately the same depth (ie 1x WGS and 30x WGS better...1584 days ago
DeepHiC: A Generative Adversarial Network for Enhancing Hi-C Data Resolution
...s of clicks. Ab initio training could be performed according to our published code. We provided trained models for various depth of low-coverage sequencing Hi-C data. The depth of input data is estimated by...1538 days ago
NucDiff: In-depth characterization and annotation of differences between two sets of DNA sequences
NucDiff locates and categorizes differences between two closely related nucleotide sequences. It is able to deal with very fragmented genomes, structural rearrangement...1475 days ago
IVA: accurate de novo assembly of RNA virus genomes
IVA (Iterative Virus Assembler) designed specifically for read pairs sequenced at highly variable depth from RNA virus samples. We tested IVA on datasets from 140 sequenced samples f...1061 days ago
Proksee: in-depth characterization and visualization of bacterial genomes
Proksee is an expert system for genome assembly, annotation and visualization. To begin using Proksee, provide a complete genome sequence, sequencing reads or a CGView/Proksee map JSON file.376 days ago