P_RNA_scaffolder: a fast and accurate genome scaffolder using paired-end RNA-sequencing reads
...-end RNA-seq to scaffold genome fragments. The method is suitable for most genomes....A-sequencing reads from target speciesies. Our method provides another practical al...sequences. The most important feature of this method is to improve the completenes...2059 days ago
STRUM: structure-based prediction of protein stability changes upon single-point mutation
STRUM is a method for predicting the fold stability change (ΔΔG) of protein molec...tructure prediction, which helps enhance the robustness and accuracy of the method and make it applicable to var...2056 days ago
2039 days ago
Rainbow: an integrated tool for efficient clustering and assembling RAD-seq reads
...fast and memory-efficient solution to clustering and assembling short reads produced by RAD-seq. First, Rainbow clusters reads using a spaced seed method. Then, Rainbow implements a h...2017 days ago
COSINE: non-seeding method for mapping long noisy sequences
Third generation sequencing (TGS) are highly promising technologies but the long and noisy reads from TGS are difficult to align using existing algorithms. Here, we present COSINE, a conceptually new method designed specifically for aligning long reads contaminated by a high level of errors.2010 days ago
EXCAVATOR: detecting copy number variants from whole-exome sequencing data
...with a novel heterogeneous hidden Markov model algorithm and a calling method that classifies genomic regio...te EXCAVATOR on three datasets and compare the results with three other methods. These analyses show that EX...1940 days ago
1923 days ago
SvABA: Genome-wide detection of structural variants and indels by local assembly
SvABA is a method for detecting structural variants in sequencing data using genome-wide local assembly. Under the hood, SvABA uses a custom implementation of SGA ...1923 days ago
geck: trio-based comparative benchmarking of variant calls
...typer and Haplotype Caller on the high-confidence SNPs of the NIST Ashkenazim trio and the two independent Platinum Genome trios. We show that our method is able to estimate diff...1804 days ago
Simka and SimkaMin are comparative metagenomics method dedicated to NGS datasets
...mer member of the Genscale team at Inria. Contact: claire dot lemaitre at inria dot fr Simka and SimkaMin are comparative metagenomics method dedicated to NGS datasets.&nb...1757 days ago