Comment on "Basic command-line to run BLAST"
...e into smaller segments, called "words," and searching for matches to those words in the database. It then expands the matches to identify longer regions of similarity, called "alignm...420 days ago
Comment on "Tools to detect synteny blocks regions among multiple genomes"
...ized using tools such as Circos or SynMap. Interpret the results: Interpret the results of the synteny analysis by identifying conserved genomic regions, identifying gene families th...422 days ago
Comment on "Sibelia: A comparative genomics tool"
...plification. Boundaries correction --------------------- Algorithm of "Sibelia" depends on presence of solid k-mers within syntenic regions. If such regions contain variations close to t...1284 days ago
Comment on "Genome in a Bottle (GIAB) Consortium"
...gh-confidence") variant calls and regions:We developed an integration p...ies to generate variant calls and regions for use in benchmarking and v...hmarks for difficult variants and regions:Structural variants: Cur...ndem repeats and difficult-to-map regions like pseudogenes and segmenta...1559 days ago
Comment on "Tools to detect synteny blocks regions among multiple genomes"
...ndle, needs to be set) and (iii) it provides a rich set of graphic outputs (notably an interactive synteny map that allows zooming in breakpoint regions).1593 days ago
Comment on "Tools to detect synteny blocks regions among multiple genomes"
Align Synteny - Beginning from completed or draft genomes, find shared syntenic regions and align them quickly while accounting for inversions, rearrangements, and duplications. http://www2.decipher.codes/AlignSynteny.html1973 days ago
Comment on "Running Trinity on RNA-seq !"
...ion analysis. Trinity provides direct support for several DE analysis methods, including edgeR, DESeq2, Limma/Voom, and ROTS. Extract coding regions using TransDecoder ...2122 days ago
Comment on "GraphMap - A highly sensitive and accurate mapper for long, error-prone reads"
...mber of match bases in an anchor. [12] -e, --error-rate FLT Approximate error rate of the input read sequences. [0.45] -g, --max-regions INT If the final number of regions exceeds this amount, the read...2291 days ago
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Comment on "Tools to detect synteny blocks regions among multiple genomes"
Thanks for such an informative blog. I notice MCScan is missing. MCScan is an algorithm able to scan multiple genomes or subgenomes in order to identify putative homologous chromosomal regions, and align these regions using genes as anchors. More at http://www.ncbi.nlm.nih.gov/pubmed/222176003672 days ago