Platypus: A Haplotype-Based Variant Caller For Next Generation Sequence Data
...and accurate variant-detection in high-throughput sequencing data. By using local realignment of reads and local assembly it achieves both high sensitivity and high specificity. Platypu...2034 days ago
Deepbinner: a signal-level demultiplexer for Oxford Nanopore reads
...r demultiplexers (e.g. Albacore and Porechop), Deepbinner identifies barcodes from the raw signal (a.k.a. squiggle) which gives it greater sensitivity and fewer unclassified reads....2001 days ago
lordFAST: sensitive and Fast Alignment Search Tool for LOng noisy Read sequencing Data
...is specifically designed to align reads generated by PacBio and potentially other SMS technologies to a reference. lordFAST not only has higher sensitivity than the available alternativ...2001 days ago
ChIPulate: A Python3 framework to simulate read counts in a ChIP-seq experiment
...ation on several outcomes of a ChIP-seq experiment, viz., the recoverability of the TF binding motif, accuracy of TF-DNA binding detection, the sensitivity of inferred TF-DNA binding st...1883 days ago
1864 days ago
Deepbinner: a signal-level demultiplexer for Oxford Nanopore reads
...other demultiplexers (e.g. Albacore and Porechop), Deepbinner identifies barcodes from the raw signal (a.k.a. squiggle) which gives it greater sensitivity and fewer unclassified reads....1561 days ago
URMAP, an ultra-fast read mapper
.... On a Genome in a Bottle (GIAB) variant calling test with 30× coverage 2×150 reads, URMAP achieves high accuracy (precision 0.998, sensitivity 0.982 and F-measure 0.990) wi...1298 days ago
MMseqs2: ultra fast and sensitive sequence search and clustering suite
...ood scalability. MMseqs2 can run 10000 times faster than BLAST. At 100 times its speed it achieves almost the same sensitivity. It can perform profile searches with the same sensitivity as PSI-BLAST at over 400 time...1218 days ago
MMseqs2: ultra fast and sensitive sequence search and clustering suite
...ood scalability. MMseqs2 can run 10000 times faster than BLAST. At 100 times its speed it achieves almost the same sensitivity. It can perform profile searches with the same sensitivity as PSI-BLAST at over 400 time...957 days ago
Metabuli 분리 improves metagenomic read classification
...DNA-based classifiers can make specific classifications, exploiting point mutations to distinguish close taxa. AA-based classifiers have higher sensitivity in detecting homology between...351 days ago