BOL

EAGER: efficient ancient genome reconstruction https://genomebiology.biomedcentral.com/articles/10.1186/s13059-016-0918-z

MGRA (Multiple Genome Rearrangements and Ancestors) is a tool for reconstruction of ancestor genomes and evolutionary history of extant genomes. It takes as an input a set of genomes represented as sequences of genes (or synteny blocks) and...

Local sequence alignment is a cornerstone of bioinformatics, allowing to compare the amino-acid sequences of different proteins, or the nucleotide sequences of different pieces of DNA. The Basic Local Alignment Search Tool (BLAST) has revolutionized...

Molecular Recording https://www.youtube.com/watch?v=o8ONjPHLr6s #DNA #Recording #Store

The gene drive bubble: New realities http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1006850 #Genes #Drive

Mulan performs multiple (2 or more) sequence alignments with an efficient and rapid "full local" alignment strategy that ensures a recapitulation of evolutionary sequence rearrangements (such as inversions and reshuffling) in any of the species. It...

Bioinformatics faculty WalkIn https://www.pdkv.ac.in/Recruitment/wii-teachervncab-040717.pdf #WalkIn #Bioinformatics

Remove "|" from fasta header. $ sed 's,|,_,g' -i file.fa #fasta #header #sed

Remove unwanted character from fasta file. sed -e '/^[^>]/s/[^ATGCatgc]/N/g' file.fa #fasta #file #header #charater

Evolution and phylogeny software http://tree.bio.ed.ac.uk/software/ #tools #software #phylogeny #evolution

FigTree is designed as a graphical viewer of phylogenetic trees and as a program for producing publication-ready figures. As with most of my programs, it was written for my own needs so may not be as polished and feature-complete as a commercial...

At UniProt search for taxonomy:mammalia in UniProtKB like this: http://www.uniprot.org/uniprot/?query=lineage%3Amammalia&sort=score There you can download a fasta file with all mammalian sequences with isoforms like...

I want to download all the mammalian protein fasta files. Is there any quick way to download all in one click? 

Transcriptome analysis