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The complete sequence of a human genome
By Neel 967 days agowww.science.org - The completed regions include all centromeric satellite arrays, recent segmental duplications, and the short arms of all five acrocentric chromosomes, unlocking these complex regions of the genome to variational and functional studies.Seal: SEquence ALignment evaluation suite
By Jit 2515 days agocompbio.case.edu - Seal is a comprehensive sequencing simulation and alignment tool evaluation suite. This software (implemented in Java) provides several utilities that can be used to evaluate alignment algorithms, including: Reading a pre-existing reference...Jabba: Hybrid Error Correction for Long Sequencing Reads
By Jit 2513 days agogithub.com - Jabba is a hybrid error correction tool to correct third generation (PacBio / ONT) sequencing data, using second generation (Illumina) data. Input Jabba takes as input a concatenated de Bruijn graph and a set of sequences: the de Bruijn graph...HECIL: A Hybrid Error Correction Algorithm for Long Reads with Iterative Learning
By Abhimanyu Singh 2152 days agogithub.com - HECIL—Hybrid Error Correction with Iterative Learning—a hybrid error correction framework that determines a correction policy for erroneous long reads, based on optimal combinations of decision weights obtained from short read...LoRMA: A tool for correcting sequencing errors in long reads
By Abhimanyu Singh 2269 days agogite.lirmm.fr - An error correction method that uses long reads only. The method consists of two phases: first, we use an iterative alignment-free correction method based on de Bruijn graphs with increasing length of k-mers, and second, the corrected reads are...Scaffolding of a bacterial genome using MinION nanopore sequencing
By Rahul Agarwal 3426 days agowww.nature.com - Second generation sequencing has revolutionized genomic studies. However, most genomes contain repeated DNA elements that are longer than the read lengths achievable with typical sequencers, so the genomic order of several generated contigs cannot...minialign: fast and accurate alignment tool for PacBio and Nanopore long reads
By Jit 2374 days agogithub.com - Minialign is a little bit fast and moderately accurate nucleotide sequence alignment tool designed for PacBio and Nanopore long reads. It is built on three key algorithms, minimizer-based index of the minimap overlapper, array-based seed chaining,...Deepbinner: a signal-level demultiplexer for Oxford Nanopore reads
By Neel 2187 days agogithub.com - Deepbinner is a tool for demultiplexing barcoded Oxford Nanopore sequencing reads. It does this with a deep convolutional neural network classifier, using many of the architectural advances that have proven successful...Now time is come to revolutionize amino acid sequencing by Nanopore technology
By Rahul Agarwal 3882 days agowww.eurekalert.org - Amino acid sequencing by Nanopore recognition tunneling method1mb long DNA with Nanopore technology
By Jit 2530 days agoLongest read of 1mb achievements with Nanopore
