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bacLIFE: an automated genome mining tool for identification of lifestyle associated genes
By BioStar 935 days agogithub.com - bacLIFE is a streamlined computational workflow that annotates bacterial genomes and performs large-scale comparative genomics to predict bacterial lifestyles and to pinpoint candidate genes, denominated lifestyle-associated genes (LAGs), and...Kamaleshwar Singh Lab
The focus of Dr. Singh’s research and teaching is on the molecular mechanistic basis for environmental carcinogen-induced genetic (DNA damage) and epigenetic changes, and susceptibility to human cancer development More at...DarkHorse
By Jit 3758 days agodarkhorse.ucsd.edu - DarkHorse is a bioinformatic method for rapid, automated identification and ranking of phylogenetically atypical proteins on a genome-wide basis. It works by selecting potential ortholog matches from a reference database of amino acid...DAGchainer: Computing Chains of Syntenic Genes in Complete Genomes
By Abhimanyu Singh 3518 days agodagchainer.sourceforge.net - The DAGchainer software computes chains of syntenic genes found within complete genome sequences. As input, DAGchainer accepts a list of gene pairs with sequence homology along with their genome coordinates. Using a scoring function which accounts...KOALA: KEGG's internal annotation tool for K number assignment of KEGG GENES using SSEARCH...
By Abhimanyu Singh 2855 days agowww.kegg.jp - KOALA (KEGG Orthology And Links Annotation) is KEGG's internal annotation tool for K number assignment of KEGG GENES using SSEARCH computation. BlastKOALA and GhostKOALA assign K numbers to the user's sequence data...
Master Thesis: Trans-membrane topology prediction through Markov based decoders
By Rahul Agarwal 4829 days agoAbstract: Background/Motivation: The dearth of structural information on alpha helical membrane protein (MPs) has hindered thus far the development of reliable knowledge –based potentials that can be used for automatic prediction of...eQuant : energy-based quality assessment of protein
By Shruti Paniwala 3391 days agobiosciences.hs-mittweida.de - Protein structures are of varying quality. Especially, in-silico modeled structures are prone to contain serious errors, which limit the usefulness and reliability of these particular protein structures.eQuant is a service for structure...STRUM: structure-based prediction of protein stability changes upon single-point mutation
By BioStar 2948 days agozhanglab.ccmb.med.umich.edu - STRUM is a method for predicting the fold stability change (ΔΔG) of protein molecules upon single-point nsSNP mutations. STRUM adopts a gradient boosting regression approch to train the Gibbs free-energy changes on a variety of features...PhD student / Bio-informatician in computational protein modeling
PhD student / Bio-informatician in computational protein modeling Job Profile You will perform research on drug/protein interaction analysis in the context of lung cancer, using computational protein modeling. You will implement existing models...
