Tags: Bioinformatics, NGS, Assembly, Validate, Approach, Tools
2811 days ago
What are the best approach that gave good results in genome projects?
I am working on genome assembly, but wordering the optimised method to achieve the best result. Your comments and suggestions are welcome.Tags: Approach, Results, Genome, Projects, NGS, Assembly
2385 days ago
GAPPadder: A Sensitive Approach for Closing Gaps on Draft Genomes with Short Sequence Reads
This software is provided ``as is” without warranty of any kind. In no event shall the author be held responsible for any damage resulting from the use of this software. The program package, including source codes, executables, and this documentation, is distributed free of charge. If you u...Tags: GAPPadder, Sensitive, Approach, Closing, Gaps, Draft, Genomes, Short, Sequence, Reads, Genome, Assembly
2197 days ago
SEX-DETector: A Probabilistic Approach to Study Sex Chromosomes in Non-Model Organisms
SEX-DETector is a probabilistic method that relies on RNAseq data from a cross (parents and progeny of each sex) to infer autosomal and sex-linked genes (genes located on the non recombining part of sex chromosomes). How does SEX-DETector work? SEX-DETector does not require prior sequencing of ...Tags: SEX-DETector, Probabilistic, Approach, Study, Sex, Chromosomes, Non-Model, Organisms
2181 days ago
Tags: PERGA, Paired-End, Read, Guided, De Novo, Assembler, Extending, Contigs, SVM, Look, Ahead, Approach, assembly
2175 days ago
miREM: an expectation-maximization approach for prioritizing miRNAs associated with gene-set
From list of genes... ... to microRNAs Using established miRNA-interaction databases, miREM combines hypergeometric and expectation-maximization algorithms to sieve through your genetic data for microRNA signatures https://bioinfo-csi.nus.edu.sg/mirem2/Tags: miREM, expectation-maximization, approach, prioritize, miRNAs, associated, gene-set
2103 days ago
wtdbg2: A fuzzy Bruijn graph approach to long noisy reads assembly
Wtdbg2 is a de novo sequence assembler for long noisy reads produced by PacBio or Oxford Nanopore Technologies (ONT). It assembles raw reads without error correction and then builds the consensus from intermediate assembly output. ./wtdbg2 -x rs -g 4.6m -t 16 -i reads.fa.gz -fo p...Tags: wtdbg2, fuzzy, Bruijn, graph, approach, long, noisy, reads, assembly
1931 days ago
RefKA: A fast and efficient long-read genome assembly approach for large and complex genomes
RefKA, a reference-based approach for long read genome assembly. This approach relies on breaking up a closely related reference genome into bins, aligning k-mers unique to each bin with PacBio reads, and then assembling each bin in parallel followed by a final bin-stitching step.Tags: RefKA, fast, efficient, long-read, genome, assembly, approach, large, complex, genomes
1479 days ago
ShadowCaster: a hybrid approach for the detection of horizontal gene transfer events in prokaryotes
ShadowCaster implements an evolutionary model to calculate Bayesian likelihoods for each ‘alien genes’ with an unusual sequence composition according to the host genome background to detect HGT events in prokaryotes. https://www.mdpi.com/2073-4425/11/7/756/htm https://shadowcaster.r...Tags: ShadowCaster, hybrid, approach, detection, horizontal, gene, transfer, prokaryotes, HGT
1405 days ago