3425 days ago
3395 days ago
1110 days ago
2946 days ago
InfoGenomeR: Integrative reconstruction of cancer genome karyotypes
InfoGenomeR is the Integrative Framework for Genome Reconstru...ivity among genomic segments at the genome-wide scale. InfoGenomeR integrates cancer purity and ploidy, total CNAs, allele-specific CNAs, and haplotype information to identif...reakpoint graph representing cancer genomes....1103 days ago
3240 days ago
GraphMap - A highly sensitive and accurate mapper for long, error-prone reads
GraphMap is a novel mapper targeted at aligning long, error-prone third-generation sequencing data.It is designed to handle Oxford Nanopore MinION 1d and 2d...idely across, or even within, sequencing runs. http://biorxiv.org/con...3231 days ago
Scaffolding of a bacterial genome using MinION nanopore sequencing
Second generation sequencing has revolutionized genomic studies. However, most genomes contain repeated DNA element...tably the Pacific Biosciences (PacBio) RS II system and the MinION system, relea...3231 days ago
Assembly and diploid architecture of an individual human genome via single-molecule technologies
The research work shows that it is now possible to integrate single-molecule and high-throu...ata to generate de novo assembled genomes that approach reference quality. https://www.genomeweb.com/sequencing-technology/researchers-combine-single-molecule-sequencing-mapping-technologies-analyze3227 days ago
Directional dominance on stature and cognition in diverse human populations
Analysis of the genomes of >350,000 individuals revealed&n...of a small though measureable association between genome-wide homozygosity and some vital complex traits... Di...his study provides evidence that increased stature and cognit...3227 days ago